Browsing NIVA Open Access Archive by Author "Asselman, Jana"
Now showing items 1-3 of 3
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Deciphering the Combined Effects of Environmental Stressors on Gene Transcription: A Conceptual Approach
Song, You; Asselman, Jana; De Schamphelaere, Karel A. C.; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)The use of classical mixture toxicity models to predict the combined effects of environmental stressors based on toxicogenomics (OMICS) data is still in its infancy. Although several studies have made attempts to implement ... -
Epigenetic, transcriptional and phenotypic responses in two generations of Daphnia magna exposed to the DNA methylation inhibitor 5-Azacytidine
Lindeman, Leif Christopher; Thaulow, Jens; Song, You; Kamstra, Jorke H; Xie, Li; Asselman, Jana; Alestrøm, Peter; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2019)The water flea Daphnia magna is a keystone species in freshwater ecosystems and has been widely used as a model organism in environmental ecotoxicology. This aquatic crustacean is sensitive to environmental stressors and ... -
High-throughput analyses and Bayesian network modeling highlight novel epigenetic Adverse Outcome Pathway networks of DNA methyltransferase inhibitor mediated transgenerational effects
Song, You; Kamstra, Jorke H; Cao, Yang; Asselman, Jana; Anglès d'Auriac, Marc; Friberg, Nikolai (Peer reviewed; Journal article, 2021)A number of epigenetic modulating chemicals are known to affect multiple generations of a population from a single ancestral exposure, thus posing transgenerational hazards. The present study aimed to establish a high-throughput ...