Browsing NIVA Open Access Archive by Author "Lillicrap, Adam David"
Now showing items 1-13 of 13
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Benzoylurea pesticides used as veterinary medicines in aquaculture: Risks and developmental effects on nontarget crustaceans
Macken, Ailbhe; Lillicrap, Adam David; Langford, Katherine (Journal article; Peer reviewed, 2015)Diflubenzuron and teflubenzuron are benzoylureas that are used in aquaculture to control sea lice. Flubenzurons have low toxicity to many marine species such as fish and algae but by their nature are likely to have significant ... -
Characterization of multiple biomarker responses using flow cytometry to improve environmental hazard assessment with the green microalgae Raphidocelis subcapitata
Almeida, Ana Catarina; Gomes, Tania; Habuda-Stanic, Mirna; Baz-Lomba, Jose Antonio; Romic, Zeljka; Turkalj, Jelena Vesligaj; Lillicrap, Adam David (Journal article; Peer reviewed, 2019)Microalgal toxicity tests using integrative endpoints as algal growth are regularly required to analyse the toxicity of potentially hazardous substances in the aquatic environment. However, these do not provide mechanistic ... -
Ciona spp. and ascidians as bioindicator organisms for evaluating effects of endocrine disrupting chemicals: A discussion paper
Beyer, Jonny; Song, You; Lillicrap, Adam David; Rodríguez-Satizábal, Simón; Chatzigeorgiou, Marios (Peer reviewed; Journal article, 2023)In context of testing, screening and monitoring of endocrine-disrupting (ED) type of environmental pollutants, tunicates could possibly represent a particularly interesting group of bioindicator organisms. These primitive ... -
Development of a hybrid Bayesian network model for predicting acute fish toxicity using multiple lines of evidence
Moe, Jannicke; Madsen, Anders; Connors, Kristin; Rawlings, Jane; Belanger, Scott; Landis, Wayne; Wolf, Raoul; Lillicrap, Adam David (Peer reviewed; Journal article, 2020)A hybrid Bayesian network (BN) was developed for predicting the acute toxicity of chemicals to fish, using data from fish embryo toxicity (FET) testing in combination with other information. This model can support the use ... -
Environmental risk assessment of veterinary medicinal products intended for use in aquaculture in Europe: the need for developing a harmonised approach
de la Casa-Resino, Irene; Empl, Michael T.; Villa, Sara; Kolar, Boris; Fabrega, Julia; Lillicrap, Adam David; Karamanlis, Xanthippos N.; Carapeto-García, Ricardo (Peer reviewed; Journal article, 2021)The current and future expansion of aquaculture production appears to be only manageable by using veterinary medicinal products (VMPs) to prevent and reduce disease outbreaks. However, only a very low number of VMPs are ... -
Evaluation of a Bayesian network for strengthening the weight of evidence to predict acute fish toxicity from fish embryo toxicity data
Lillicrap, Adam David; Moe, Jannicke; Wolf, Raoul; Connors, Kristin A.; Rawlings, Jane M.; Landis, Wayne G.; Madsen, Anders L.; Belanger, Scott E. (Peer reviewed; Journal article, 2020)The use of sh embryo toxicity (FET) data for hazard assessments of chemicals, in place of acute sh toxicity (AFT) data, has long been the goal for many environmental scientists. The FET test was rst proposed as a ... -
Limitations and Uncertainties of Acute Fish Toxicity Assessments Can Be Reduced Using Alternative Methods
Paparella, Martin; Scholz, Stefan; Belanger, Scott; Braunbeck, Thomas; Bicherel, Pascal; Connors, Kristin; Faßbender, Christopher; Halder, Marlies; Lillicrap, Adam David; Liska, Roman; Schirmer, Kristin; Stoddart, Gilly; Thomas, Paul; Walter-Rohde, Susanne (Peer reviewed; Journal article, 2021)Information about acute fish toxicity is routinely required in many jurisdictions for environmental risk assessment of chemicals. This information is typically obtained using a 96-hour juvenile fish test for lethality ... -
OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing
Busquet, François; Strecker, Ruben; Rawlings, Jane M.; Belanger, Scott E.; Braunbeck, Thomas; Carr, Gregory J.; Cenijn, Peter; Fochtman, Przemyslaw; Gourmelon, Anne; Hübler, Nicole; Kleensang, André; Knöbel, Melanie; Kussatz, Carola; Legler, Juliette; Lillicrap, Adam David; Martínez-Jerónimo, Fernando; Polleichtner, Christian; Rzodeczko, Helena; Salinas, Edward; Schneider, Katharina E.; Scholz, Stefan; van den Brandhof, Evert-Jan; van der Ven, Leo T.M.; Walter-Rohde, Susanne; Weigt, Stefan; Witters, Hilda; Halder, Marlies (Journal article; Peer reviewed, 2014)The OECD validation study of the zebrafish embryo acute toxicity test (ZFET) for acute aquatic toxicity testing evaluated the ZFET reproducibility by testing 20 chemicals at 5 different concentrations in 3 independent runs ... -
Oppdatert risikovurdering av sedimenter og overvåking med vektpå PAH av det nære sjøområdet til Elkem i Kristiansand i 2013
Næs, Kristoffer; Håvardstun, Jarle; Oug, Eivind; Beyer, Jonny; Bakke, Torgeir Heggelund; Heiaas, Harald; Lillicrap, Adam David; Allan, Ian (NIVA-rapport;6664, Research report, 2014)Bedriftene Elkem Carbon AS og Elkem Solar AS gjennomfører et overvåkingsprogram i det bedriftsnære sjøområdet i Kristiansandsfjorden. Programmet supplerer og er koplet opp mot myndighetenes generelle overvåking av ... -
Repeatability and reproducibility of the RTgill-W1 cell line assay for predicting fish acute toxicity
Fischer, Melanie; Belanger, Scott E.; Berckmans, Pascale; Bernhard, Mary J.; Bláha, Ludek; Coman Schmid, Diana E.; Dyer, Scott D.; Haupt, Tina; Hermens, Joop L.M.; Hultman, Maria Thérése; Laue, Heike; Lillicrap, Adam David; Mlnaříková, Marie; Natsch, Andreas; Novák, Jirí; Sinnige, Theo L.; Tollefsen, Knut-Erik; Niederhäusern, Valentin von; Witters, Hilda; Zupanic, Anze; Schirmer, Kristin (Journal article; Peer reviewed, 2019)Predicting fish acute toxicity of chemicals in vitro is an attractive alternative method to the conventional approach using juvenile and adult fish. The rainbow trout (Oncorhynchus mykiss) cell line assay with RTgill-W1 ... -
Specific toxicity of azithromycin to the freshwater microalga Raphidocelis subcapitata
Almeida, Ana Catarina; Gomes, Tânia; Baz-Lomba, Jose Antonio; Lillicrap, Adam David (Peer reviewed; Journal article, 2021)Pharmaceuticals are produced to inflict a specific physiological response in organisms. However, as only partially metabolized after administration, these types of compounds can also originate harmful side effects to ... -
Unravelling reasons for variability in the OECD 306 marine biodegradation test
Wennberg, Aina Charlotte; Meland, Sondre; Grung, Merete; Lillicrap, Adam David (Peer reviewed; Journal article, 2022)The recommended test for assessing if a chemical can be biodegraded in the marine environment is performed according to the Organisation for Economic Cooperation and Development Marine biodegradation test guideline (OECD ... -
Weight of evidence tools in the prediction of acute fish toxicity
Belanger, Scott E.; Lillicrap, Adam David; Moe, S. Jannicke; Wolf, Raoul; Connors, Kristin; Embry, Michelle R. (Peer reviewed; Journal article, 2022)Acute fish toxicity (AFT) is a key endpoint in nearly all regulatory implementations of environmental hazard assessments of chemicals globally. Although it is an early tier assay, the AFT assay is complex and uses many ...