Browsing NIVA Open Access Archive by Author "Xie, Li"
Now showing items 1-18 of 18
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Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Tollefsen, Knut Erik; Alonzo, Frederic; Beresford, Nicholas A.; Brede, Dag Anders; Dufourcq-Sekatcheff, Elizabeth; Gilbin, Rodolphe; Horemans, Nele; Hurem, Selma; Laloi, Patrick; Maremonti, Erica; Oughton, Deborah Helen; Simon, Olivier; Song, You; Wood, Michael; Xie, Li; Frelon, Sandrine (Peer reviewed; Journal article, 2022)Reproductive effects of ionizing radiation in organisms have been observed under laboratory and field conditions. Such assessments often rely on associations between exposure and effects, and thus lacking a detailed ... -
Effects of artificial ultraviolet B radiation on the macrophyte Lemna minor: a conceptual study for toxicity pathway characterization
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Johnsen, Bjørn; Olsen, Jorunn Elisabeth; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Macrophytes inhabit waterways around the world and are used in hydroponics or aquaponics for different purposes such as feed and wastewater treatment and are thus exposed to elevated levels of UVB from natural and artificial ... -
Epigenetic, transcriptional and phenotypic responses in Daphnia magna exposed to low-level ionizing radiation
Thaulow, Jens; Song, You; Lindeman, Leif C; Kamstra, Jorke H; YeonKyeong, Lee; Xie, Li; Aleström, Peter; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Ionizing radiation is known to induce oxidative stress and DNA damage as well as epigenetic effects in aquatic organisms. Epigenetic changes can be part of the adaptive responses to protect organisms from radiation-induced ... -
Epigenetic, transcriptional and phenotypic responses in two generations of Daphnia magna exposed to the DNA methylation inhibitor 5-Azacytidine
Lindeman, Leif Christopher; Thaulow, Jens; Song, You; Kamstra, Jorke H; Xie, Li; Asselman, Jana; Alestrøm, Peter; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2019)The water flea Daphnia magna is a keystone species in freshwater ecosystems and has been widely used as a model organism in environmental ecotoxicology. This aquatic crustacean is sensitive to environmental stressors and ... -
Gamma radiation induces dose-dependent oxidative stress and transcriptional alterations in the freshwater crustacean Daphnia magna
Gomes, Tania; Song, You; Brede, Dag Anders; Xie, Li; Gutzkow, Kristine Bjerve; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)Among aquatic organisms, invertebrate species such as the freshwater crustacean Daphnia magna are believed to be sensitive to gamma radiation, although information on responses at the individual, biochemical and molecular ... -
Integrative assessment of low-dose gamma radiation effects on Daphnia magna reproduction: Toxicity pathway assembly and AOP development
Song, You; Xie, Li; Lee, YeonKyeong; Brede, Dag Anders; Lyne, Fern; Kassaye, Yetneberk Ayalew; Thaulow, Jens; Caldwell, Gary S.; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)High energy gamma radiation is potentially hazardous to organisms, including aquatic invertebrates. Although extensively studied in a number of invertebrate species, knowledge on effects induced by gamma radiation is to a ... -
Interlaboratory Validation of Toxicity Testing Using the Duckweed Lemna minor Root-Regrowth Test
Park, Jihae; Yoo, Eun-Jin; Shin, Kisik; Depuydt, Stephen; Li, Wei; Appenroth, Klaus-J.; Lillicrap, Adam D.; Xie, Li; Lee, Hojun; Kim, Geehyoung; De Saeger, Jonas; Choi, Soyeon; Kim, Geonhee; Brown, Murray T.; Han, Taejun (Peer reviewed; Journal article, 2022)The common duckweed (Lemna minor), a freshwater monocot that floats on the surfaces of slow-moving streams and ponds, is commonly used in toxicity testing. The novel Lemna root- regrowth test is a toxicity test performed ... -
Linking mode of action of the model respiratory and photosynthesis uncoupler 3,5-dichlorophenol to adverse outcomes in Lemna minor
Xie, Li; Gomes, Tania; Solhaug, Knut Asbjørn; Song, You; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)Standard chemical toxicity testing guidelines using aquatic plant Lemna minor have been developed by several international standardisation organisations. Although being highly useful for regulatory purposes by focusing on ... -
The MicroClimate Screen – A microscale climate exposure system for assessing the effect of CO2, temperature and UV on marine microalgae
Xie, Li; Macken, Ailbhe; Johnsen, Bjørn; Norli, Marit; Skogan, Odd Arne Segtnan; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2022)Global warming and anthropogenic activities are changing the ocean, inducing profound impacts on marine life and ecosystems from changing physical and chemical factors in and above the water column. Rising surface temperatures, ... -
Modes of action and adverse effects of gamma radiation in an aquatic macrophyte Lemna minor
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Brede, Dag Anders; Lind, Ole Christian; Salbu, Brit; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2019)High dose rates of ionizing radiation have been reported to cause adverse effects such as reduction in reproduction and growth, and damage to protein and lipids in primary producers. However, the relevant effects of ionizing ... -
Multiomics Point of Departure (moPOD) Modeling Supports an Adverse Outcome Pathway Network for Ionizing Radiation
Song, You; Zheng, Keke; Brede, Dag Anders; Gomes, Tania; Xie, Li; Kassaye, Yetneberk Ayalew; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2023)While adverse biological effects of acute high-dose ionizing radiation have been extensively investigated, knowledge on chronic low-dose effects is scarce. The aims of the present study were to identify hazards of low-dose ... -
No evidence of a protective or cumulative negative effect of UV-B on growth inhibition induced by gamma radiation in Scots pine (Pinus sylvestris) seedlings
Blagojevic, Dajana; Lee, YeonKyeong; Xie, Li; Brede, Dag A; Nybakken, Line; Lind, Ole Christian; Tollefsen, Knut Erik; Salbu, Brit; Solhaug, Knut Asbjørn; Olsen, Jorunn E (Peer reviewed; Journal article, 2019)Exposure to ambient UV-B radiation may prime protective responses towards various stressors in plants, though information about interactive effects of UV-B and gamma radiation is scarce. Here, we aimed to test whether UV-B ... -
De novo Development of a Quantitative Adverse Outcome Pathway (qAOP) Network for Ultraviolet B (UVB) Radiation Using Targeted Laboratory Tests and Automated Data Mining
Song, You; Xie, Li; Lee, YeonKyeong; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Ultraviolet B (UVB) radiation is a natural non-chemical stressor posing potential hazards to organisms such as planktonic crustaceans. The present study was conducted to revisit the lethal effects of UVB on crustaceans, ... -
Quantification of an Adverse Outcome Pathway Network by Bayesian Regression and Bayesian Network Modeling
Moe, S. Jannicke; Wolf, Raoul; Xie, Li; Landis, Wayne G.; Kotamäki, Niina; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)The adverse outcome pathway (AOP) framework has gained international recognition as a systematic approach linking mechanistic processes to toxicity endpoints. Nevertheless, successful implementation into risk assessments ... -
Radiation effects and ecological processes in a freshwater microcosm
Hevrøy, Tanya H; Golz, Anna-Lea; Hansen, Elisabeth L; Xie, Li; Bradshaw, Clare (Peer reviewed; Journal article, 2019)Ecosystem response to gamma radiation exposure depends on the different species sensitivities and the multitude of direct and indirect pathways by which individual organisms can be affected, including the potential for ... -
Sensitivity of the green algae Chlamydomonas reinhardtii to gamma radiation: Photosynthetic performance and ROS formation
Gomes, Tania; Xie, Li; Brede, Dag Anders; Lind, Ole Christian; Solhaug, Knut Asbjørn; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017)The aquatic environment is continuously exposed to ionizing radiation from both natural and anthropogenic sources, making the characterization of ecological and health risks associated with radiation of large importance. ... -
Ultraviolet B modulates gamma radiation-induced stress responses in Lemna minor at multiple levels of biological organisation
Xie, Li; Song, You; Petersen, Karina; Solhaug, Knut Asbjørn; Lind, Ole Christian; Brede, Dag Anders; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2022)Elevated levels of ionizing and non-ionizing radiation may co-occur and pose cumulative hazards to biota. However, the combined effects and underlying toxicity mechanisms of different types of radiation in aquatic plants ... -
Whole-Organism Transcriptomic Analysis Provides Mechanistic Insight into the Acute Toxicity of Emamectin Benzoate in Daphnia magna
Song, You; Rundberget, Thomas; Evenseth, Linn Mari; Xie, Li; Gomes, Tania; Høgåsen, Tore; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2016)Emamectin benzoate (EMB) is an antisea lice chemical widely used in the aquaculture that may also unintentionally affect nontarget crustaceans in the environment. Although the adverse effects of this compound are well ...