Blar i NIVA Open Access Archive på forfatter "Brede, Dag Anders"
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Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Tollefsen, Knut Erik; Alonzo, Frederic; Beresford, Nicholas A.; Brede, Dag Anders; Dufourcq-Sekatcheff, Elizabeth; Gilbin, Rodolphe; Horemans, Nele; Hurem, Selma; Laloi, Patrick; Maremonti, Erica; Oughton, Deborah Helen; Simon, Olivier; Song, You; Wood, Michael; Xie, Li; Frelon, Sandrine (Peer reviewed; Journal article, 2022)Reproductive effects of ionizing radiation in organisms have been observed under laboratory and field conditions. Such assessments often rely on associations between exposure and effects, and thus lacking a detailed ... -
Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
Hurem, Selma; Gomes, Tania; Brede, Dag Anders; Mayer, Ian; Lobert, Viola; Mutoloki, Stephen; Gutzkow, Kristine Bjerve; Teien, Hans-Christian; Oughton, Deborah Helen; Alestrøm, Peter; Lyche, Jan Ludvig (Journal article; Peer reviewed, 2018)The biological effects of gamma radiation may exert damage beyond that of the individual through its deleterious effects on reproductive function. Impaired reproductive performance can result in reduced population size ... -
Gamma radiation induces dose-dependent oxidative stress and transcriptional alterations in the freshwater crustacean Daphnia magna
Gomes, Tania; Song, You; Brede, Dag Anders; Xie, Li; Gutzkow, Kristine Bjerve; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)Among aquatic organisms, invertebrate species such as the freshwater crustacean Daphnia magna are believed to be sensitive to gamma radiation, although information on responses at the individual, biochemical and molecular ... -
Integrative assessment of low-dose gamma radiation effects on Daphnia magna reproduction: Toxicity pathway assembly and AOP development
Song, You; Xie, Li; Lee, YeonKyeong; Brede, Dag Anders; Lyne, Fern; Kassaye, Yetneberk Ayalew; Thaulow, Jens; Caldwell, Gary S.; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)High energy gamma radiation is potentially hazardous to organisms, including aquatic invertebrates. Although extensively studied in a number of invertebrate species, knowledge on effects induced by gamma radiation is to a ... -
Modes of action and adverse effects of gamma radiation in an aquatic macrophyte Lemna minor
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Brede, Dag Anders; Lind, Ole Christian; Salbu, Brit; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2019)High dose rates of ionizing radiation have been reported to cause adverse effects such as reduction in reproduction and growth, and damage to protein and lipids in primary producers. However, the relevant effects of ionizing ... -
Multiomics Point of Departure (moPOD) Modeling Supports an Adverse Outcome Pathway Network for Ionizing Radiation
Song, You; Zheng, Keke; Brede, Dag Anders; Gomes, Tania; Xie, Li; Kassaye, Yetneberk Ayalew; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2023)While adverse biological effects of acute high-dose ionizing radiation have been extensively investigated, knowledge on chronic low-dose effects is scarce. The aims of the present study were to identify hazards of low-dose ... -
Sensitivity of the green algae Chlamydomonas reinhardtii to gamma radiation: Photosynthetic performance and ROS formation
Gomes, Tania; Xie, Li; Brede, Dag Anders; Lind, Ole Christian; Solhaug, Knut Asbjørn; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017)The aquatic environment is continuously exposed to ionizing radiation from both natural and anthropogenic sources, making the characterization of ecological and health risks associated with radiation of large importance. ... -
Ultraviolet B modulates gamma radiation-induced stress responses in Lemna minor at multiple levels of biological organisation
Xie, Li; Song, You; Petersen, Karina; Solhaug, Knut Asbjørn; Lind, Ole Christian; Brede, Dag Anders; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2022)Elevated levels of ionizing and non-ionizing radiation may co-occur and pose cumulative hazards to biota. However, the combined effects and underlying toxicity mechanisms of different types of radiation in aquatic plants ...