• New Approach Methodologies for the Endocrine Activity Toolbox: Environmental Assessment for Fish and Amphibians 

      Mitchell, Constance A.; Burden, Natalie; Bonnell, Mark; Hecker, Markus; Hutchinson, Thomas H.; Jagla, Magdalena; LaLone, Carlie A.; Lagadic, Laurent; Lynn, Scott G.; Shore, Bryon; Song, You; Vliet, Sara M.; Wheeler, James R.; Embry, Michelle R. (Peer reviewed; Journal article, 2023)
      Multiple in vivo test guidelines focusing on the estrogen, androgen, thyroid, and steroidogenesis pathways have been developed and validated for mammals, amphibians, or fish. However, these tests are resource-intensive and ...
    • Weight of evidence tools in the prediction of acute fish toxicity 

      Belanger, Scott E.; Lillicrap, Adam David; Moe, S. Jannicke; Wolf, Raoul; Connors, Kristin; Embry, Michelle R. (Peer reviewed; Journal article, 2022)
      Acute fish toxicity (AFT) is a key endpoint in nearly all regulatory implementations of environmental hazard assessments of chemicals globally. Although it is an early tier assay, the AFT assay is complex and uses many ...