• Changes in drug use in European cities during early COVID-19 lockdowns – A snapshot from wastewater analysis 

      Been, Frederic; Emke, Erik; Matias, João; Baz-Lomba, Jose Antonio; Boogaerts, Tim; Castiglioni, Sara; Campos-Mañas, Marina; Celma, Alberto; Covaci, Adrian; de Voogt, Pim; Hernández, Félix; Kasprzyk-Hordern, Barbara; ter Laak, Thomas; Reid, Malcolm James; Salgueiro-González, Noelia; Steenbeek, Ruud; van Nuijs, Alexander L.N.; Zuccato, Ettore; Bijlsma, Lubertus (Peer reviewed; Journal article, 2021)
      The COVID-19 outbreak has forced countries to introduce severe restrictive measures to contain its spread. In particular, physical distancing and restriction of movement have had important consequences on human behaviour ...
    • Comparative measurement and quantitative risk assessment of alcohol consumption through wastewater-based epidemiology: An international study in 20 cities 

      Ryu, Yeonsuk; Barceló, Damia; Barron, Leon P.; Bijlsma, Lubertus; Castiglioni, Sara; de Voogt, Pim; Emke, Erik; Hernández, Félix; Lai, Foon Yin; Lopes, Alvaro; de Alda, Miren López; Mastroianni, Nicola; Munro, Kelly; O'Brien, Jake; Ort, Christoph; Plosz, Benedek; Reid, Malcolm J; Yargeau, Viviane; Thomas, Kevin V (Journal article; Peer reviewed, 2016)
      Quantitative measurement of drug consumption biomarkers in wastewater can provide objective information on community drug use patterns and trends. This study presents the measurement of alcohol consumption in 20 cities ...
    • Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities 

      Baz-Lomba, Jose Antonio; Salvatore, Stefania; Gracia-Lor, Emma; Bade, Richard; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Hernandez, Félix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek G.; Ramin, Pedram; Reid, Malcolm; Rousis, Nikolaos I.; Ryu, Yeonsuk; de Voogt, Pim; Bramness, Jørgen; Thomas, Kevin (Journal article; Peer reviewed, 2016)
      Background: Monitoring the scale of pharmaceuticals, illicit and licit drugs consumption is important to assess the needs of law enforcement and public health, and provides more information about the different trends within ...
    • Comparison of phosphodiesterase type V inhibitors use in eight European cities through analysis of urban wastewater 

      Causanilles, Ana; Rojas Cantillano, Daniela; Emke, Erik; Bade, Richard; Baz-Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Gracia-Lor, Emma; Hernández, Félix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander L. N.; Plosz, Benedek G; Ramin, Pedram; Rousis, Nikolaos I.; Ryu, Yeonsuk; Thomas, Kevin V; de Voogt, Pim (Journal article; Peer reviewed, 2018)
      In this work a step forward in investigating the use of prescription drugs, namely erectile dysfunction products, at European level was taken by applying the wastewater-based epidemiology approach. 24-h composite samples ...
    • Drug Use by Music Festival Attendees: A Novel Triangulation Approach Using Self-Reported Data and Test Results of Oral Fluid and Pooled Urine Samples 

      Gjerde, Hallvard; Gjersing, Linn; Baz-Lomba, Jose Antonio; Bijlsma, Lubertus; Salgueiro-González, Noelia; Furuhaugen, Håvard; Bretteville-Jensen, Anne Line; Hernández, Félix; Castiglioni, Sara; Amundsen, Ellen Johanna; Zuccato, Ettore (Journal article; Peer reviewed, 2019)
      Background: Self-reported data are commonly used when investigating illicit substance use. However, self-reports have well-known limitations such as limited recall and socially desirable responding. Mislabeling or adulteration ...
    • Enantiomeric profiling of chiral illicit drugs in a pan-European study 

      Castrignanò, Erika; Yang, Zhugen; Bade, Richard; Baz-Lomba, Jose A; Castiglioni, Sara; Causanilles, Ana; Covaci, Adrian; Gracia-Lor, Emma; Hernandez, Félix; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander L N; Ort, Christoph; Plosz, Benedek G; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara (Journal article; Peer reviewed, 2018)
      The aim of this paper is to present the first study on spatial and temporal variation in the enantiomeric profile of chiral drugs in eight European cities. Wastewater-based epidemiology (WBE) and enantioselective analysis ...
    • Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use 

      Ryu, Yeonsuk; Gracia-Lor, Emma; Bade, Richard; Baz-Lomba, J A; Bramness, Jørgen G; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; De Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Ort, Christoph; Plosz, Benedek G; Ramin, Pedram; Rousis, Nikolaos I.; Reid, Malcolm J; Thomas, Kevin V (Journal article; Peer reviewed, 2016)
      Wastewater analysis has been demonstrated to be a complementary approach for assessing the overall patterns of drug use by a population while the full potential of wastewater-based epidemiology has yet to be explored. ...
    • Mass spectrometric strategies for the investigation of biomarkers of illicit drug use in wastewater 

      Hernández, Félix; Castiglioni, Sara; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Kasprzyk-Hordern, Barbara; Ort, Christoph; Reid, Malcolm; Sancho, Juan V.; Thomas, Kevin V; van Nuijs, Alexander L.N.; Zuccato, Ettore; Bijlsma, Lubertus (Journal article; Peer reviewed, 2018)
      The analysis of illicit drugs in urban wastewater is the basis of wastewater‐based epidemiology (WBE), and has received much scientific attention because the concentrations measured can be used as a new non‐intrusive tool ...
    • Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis 

      Bijlsma, Lubertus; Celma, Alberto; Castiglioni, Sara; Salgueiro-González, Noelia; Bou-Iserte, Lledó; Baz Lomba, Jose Antonio; Reid, Malcolm James; Dias, Mário João Rodrigues; Lopes, Alvaro; Matias, João; Pastor-Alcañiz, Laura; Radonić, Jelena L.; Turk Sekulic, Sekulic; Shine, Trevor; van Nuijs, Alexander L.N.; Hernández, Félix; Zuccato, Ettore (Peer reviewed; Journal article, 2020)
      The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily ...
    • Multi-year inter-laboratory exercises for the analysis of illicit drugs and metabolites in wastewater: Development of a quality control system 

      van Nuijs, Alexander L.N.; Lai, Foon Yin; Been, Frederic; Andres-Costa, Maria Jesus; Barron, Leon; Baz-Lomba, Jose Antonio; Berset, Jean-Daniel; Benaglia, Lisa; Bijlsma, Lubertus; Burgard, Dan; Castiglioni, Sara; Christophoridis, Christophoros; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Fatta-Kassinos, Despo; Fick, Jerker; Hernandez, Felix; Gerber, Cobus; González-Mariño, Iria; Grabic, Roman; Gunnar, Teemu; Kannan, Kurunthachalam; Karolak, Sara; Kasprzyk-Hordern, Barbara; Kokot, Zenon; Krizman-Matasic, Ivona; Li, Angela; Li, Xiqing; Löve, Arndis S.C.; Lopez de Alda, Miren; McCall, Ann-Kathrin; Meyer, Markus R.; Oberacher, Herbert; O'Brien, Jake; Quintana, Jose Benito; Reid, Malcolm James; Schneider, Serge; Simoes, Susana Sadler; Thomaidis, Nikolaos S.; Thomas, Kevin V; Yargeau, Viviane; Ort, Christoph (Journal article; Peer reviewed, 2018)
      Thirty-seven laboratories from 25 countries present the development of an inter-laboratory testing scheme for the analysis of seven illicit drug residues in standard solutions, tap- and wastewater. Almost 10 000 concentration ...
    • Spatial differences and temporal changes in illicit drug use in Europe quantified by wastewater analysis 

      Ort, Christoph; van Nuijs, Alexander L. N.; Berset, Jean-Daniel; Bijlsma, Lubertus; Castiglioni, Sara; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Fatta-Kassinos, Despo; Griffiths, Paul; Hernández, Félix; González-Mariño, Iria; Grabic, Roman; Kasprzyk-Hordern, Barbara; Mastroianni, Nicola; Meierjohann, Axel; Nefau, Thomas; Östman, Marcus; Pico, Yolanda; Racamonde, Ines; Reid, Malcolm James; Slobodnik, Jaroslav; Terzic, Senka; Thomaidis, Nikolaos; Thomas, Kevin V (Journal article; Peer reviewed, 2014)
    • Spatio-temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring 

      González-Mariño, Iria; Baz-Lomba, Jose Antonio; Alygizakis, Nikiforos; Andres-Costa, Maria Jesus; Bade, Richard; Bannwarth, Anne; Barron, Leon-P; Been, Frederic; Benaglia, Lisa; Berset, Jean-Daniel; Bijlsma, Lubertus; Bodík, Igor; Brenner, Asher; Brock, Andreas L.; Burgard, Dan; Castrignanò, Erika; Celma, Alberto; Christophoridis, Christophoros; Covaci, Adrian; Emke, Erik; Devault, Damien A.; Dias, Mário J.; Esseiva, Pierre; Fatta-Kassinos, Despo; Fedorova, Ganna; Fytianos, Konstantinos; Gerber, Cobus; Grabic, Roman; Gracia-Lor, Emma; Grüner, Stefan; Gunnar, Teemu; Hapeshi, Evroula; Heath, Ester; Helm, Björn; Hernández, Félix; Kankaanpaa, Aino; Karolak, Sara; Kasprzyk-Hordern, Barbara; Krizman-Matasic, Ivona; Lai, Foon Yin; Lechowicz, Wojciech; Lopes, Alvaro; de Alda, Miren López; López-García, Ester; Löve, Arndís S. C.; Mastroianni, Nicola; McEneff, Gillian L.; Montes, Rosa; Munro, Kelly; Nefau, Thomas; Oberacher, Herbert; O'Brien, Jake; Oertel, Reinhard; Ólafsdóttir, Kristín; Pico, Yolanda; Plósz, Benedek G.; Polesel, Fabio; Postigo, Cristina; Quintana, José Benito; Ramin, Pedram; Reid, Malcolm James; Rice, Jack; Rodil, Rosario; Salgueiro-González, Noelia; Schubert, Sara; Senta, Ivan; Simoes, Susana Sadler; Sremacki, Maja M.; Styszko, Katarzyna; Terzic, Senka; Thomaidis, Nikolaos S.; Thomas, Kevin V; Tscharke, Benjamin; Udrisard, Robin; van Nuijs, Alexander L.N.; Yargeau, Viviane; Zuccato, Ettore; Castiglioni, Sara; Ort, Christoph (Peer reviewed; Journal article, 2020)
      Background and aims. Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess ...
    • Water-borne pharmaceuticals reduce phenotypic diversity and response capacity of natural phytoplankton communities 

      Pomati, Francesco; Jokela, Jukka; Castiglioni, Sara; Thomas, Mridul K; Nizzetto, Luca (Journal article; Peer reviewed, 2017)
      Chemical micropollutants occur worldwide in the environment at low concentrations and in complex mixtures, and how they affect the ecology of natural systems is still uncertain. Dynamics of natural communities are driven ...