Blar i NIVA Open Access Archive på forfatter "Cronin, Mark T.D."
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In silico identification of chemicals capable of binding to the ecdysone receptor
Mellor, Claire L.; Tollefsen, Knut-Erik; LaLone, Carlie; Cronin, Mark T.D.; Firman, James W. (Peer reviewed; Journal article, 2020)The process of molting, known alternatively as ecdysis, is a feature integral in the life cycles of species across the arthropod phylum. Regulation occurs as a function of the interaction of ecdysteroid hormones with the ... -
A review of quantitative structure-activity relationship modelling approaches to predict the toxicity of mixtures
Belfield, Samuel J.; Firman, James W.; Enoch, Steven J.; Madden, Judith C.; Tollefsen, Knut-Erik; Cronin, Mark T.D. (Peer reviewed; Journal article, 2022)Exposure to chemicals generally occurs in the form of mixtures. However, the great majority of the toxicity data, upon which chemical safety decisions are based, relate only to single compounds. It is currently unfeasible ...