Blar i Scientific publications på tidsskrift "Computational Toxicology"
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In silico site-directed mutagenesis of the Daphnia magna ecdysone receptor identifies critical amino acids for species-specific and inter-species differences in agonist binding
(Journal article; Peer reviewed, 2019)Molting is an essential process in the life cycle of arthropods and is regulated by complex neuroendocrine pathways where activation of the ecdysone receptor (EcR) plays a major role. The EcR forms a non-covalent heterodimer ... -
A review of quantitative structure-activity relationship modelling approaches to predict the toxicity of mixtures
(Peer reviewed; Journal article, 2022)Exposure to chemicals generally occurs in the form of mixtures. However, the great majority of the toxicity data, upon which chemical safety decisions are based, relate only to single compounds. It is currently unfeasible ...