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dc.contributor.authorHylland, K.nb_NO
dc.contributor.authorRuus, A.nb_NO
dc.contributor.authorBørseth, J.F.nb_NO
dc.contributor.authorBechmann, R.nb_NO
dc.contributor.authorBarsiene, J.nb_NO
dc.contributor.authorGrung, M.nb_NO
dc.contributor.authorTollefsen, K.nb_NO
dc.contributor.authorMyhre, L.P.nb_NO
dc.contributor.otherHylland, K. - Project managernb_NO
dc.date.accessioned2014-08-01T10:50:24Z
dc.date.available2014-08-01T10:50:24Z
dc.date.issued2006nb_NO
dc.identifier5205nb_NO
dc.identifier.isbn82-577-4924-9nb_NO
dc.identifier.issn1894-7948nb_NO
dc.identifier.urihttp://hdl.handle.net/11250/213210
dc.descriptionÅrsliste 2006nb_NO
dc.description.abstractBiological effects are increasingly used to monitor impacts of contaminants in marine ecosystems. Biomarkers have been defined as ”biochemical, cellular, physiological or behavioural variations in the tissue or body fluids or at the level of whole organism that provide evidence of exposure to chemical pollutants, and may also indicate a toxic effect”. The biomarkers reviewed here were PAH bile metabolites, cytochrome P4501A, glutathione S-transferase, markers for DNA damage (adducts, alkaline unwinding, Comet assay), micronucleus formation, peroxisomal proliferation, acetyl cholinesterase inhibition, metallothionein, vitellogenin and delta-aminolevulinic acid dehydratase. Focus for the review was dose-response relationships, confounding factors, links to population effects, baseline values, assessment criteria and quality assurance for the relevant biomarker. Whereas correlative links to population-relevant effects have been found for some biomarkers, e.g. biomarkers for DNA damage, most biomarkers are generally more useful as markers for possible impacts elsewhere in ecosystems.nb_NO
dc.description.sponsorshipOLFnb_NO
dc.publisherNorsk institutt for vannforskningnb_NO
dc.relation.ispartofseriesNIVA-rapport;5205nb_NO
dc.rightsNavngivelse-IkkeKommersiell-DelPåSammeVilkår 3.0 Norgenb_NO
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/no/nb_NO
dc.subjectøkotoksikologi og risikovurderingernb_NO
dc.titleBiomarkers in monitoring - a reviewnb_NO
dc.typeResearch reportnb_NO
dc.rights.holderNorsk institutt for vannforskning/Norwegian institute for water researchnb_NO
dc.subject.nsiVDP::Matematikk og naturvitenskap: 400nb_NO
dc.source.pagenumber106nb_NO
dc.subject.keywordbiomarkernb_NO
dc.subject.keywordovervåkingnb_NO
dc.subject.keywordoffshorenb_NO
dc.subject.keywordøkologiske effekternb_NO
dc.subject.keywordbiomarkernb_NO
dc.subject.keywordmonitoringnb_NO
dc.subject.keywordoffshorenb_NO
dc.subject.keywordecological impactnb_NO
dc.relation.projectO-25302nb_NO


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